Scientist in AAV Synthetic Biology & Gene Therapy 100%, Basel, fixed-term
ETH Zürich
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Scientist in AAV Synthetic Biology & Gene Therapy
100%, Basel, fixed-term
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The Biotechnology and Bioengineering group at the Department of Biosystems Science and Engineering (D-BSSE) of ETH
Zurich in Basel is looking for scientists who are eager to make a difference. If you're someone who thrives on
innovation and wants to be part of something new and exciting, we'd love to hear from you! We're on the lookout for
talented individuals to join us in launching a new venture focused on cutting-edge research in scalable recombinant
Adeno-associated virus (rAAV) manufacturing and closed-loop gene therapies for inborn metabolic disorders.
The D-BSSE is a special place where different fields of study come together in a beautiful harmony. It's the first of
its kind at the Swiss Federal Institute of Technology, ETH Zurich, and its mission is to encourage progress in the
fields of Systems Biology, Biotechnology, and Synthetic Biology. Here, groups working on theoretical biology,
experimental biology, and engineering work together, sharing their passion and knowledge to make the world a better
place. The D-BSSE is based in beautiful Basel, Switzerland. It's right in the heart of the Biovalley, a tri-national
region that's home to 40% of the global life science industry. This includes several pharma giants, which makes it a
special place for high-leverage translational research.
Project background
Our group uses state-of-the-art Synthetic Biology principles to engineer human cells and develop advanced gene and
cell therapies targeting cancer, as well as metabolic, neurodegenerative, autoimmune and infectious diseases. For more
information, please consult our webpage and published work.
Job description
We're working on a really exciting project together! Our goal is to take synthetic biology tools and turn them into
amazing new AAV-based therapies. We're striving to make them safer, more effective, and easier to produce in large
quantities. We're working hard to overcome some of the challenges we face in the gene therapy field. This includes
finding ways to produce large amounts of AAV vectors, as well as creating gene therapies that can adjust to the signs
of diseases and keep the levels of the therapeutic protein just right. You'll get to be a part of developing,
validating, and integrating these technologies, and help shape the roadmap towards clinical translation.
Profile
We're on the lookout for exceptional scientists who are passionate about commercializing startup technologies. You're
a creative and highly motivated scientist who does well in a high-power scientific environment. You're excited by the
opportunity to create and implement cutting-edge technologies. In addition, you have:
- A PhD in synthetic biology, bioengineering, biotechnology or a related field
- A proven track and publication record in academia or industry
- Experience with mammalian cell engineering, AAV vector design, production, and purification, synthetic gene circuits
and inducible expression systems, high-throughput screening and advanced molecular cloning, and in vivo preclinical
models
- A strong entrepreneurial mindset
- A collaborative, motivated and excelling attitude
Workplace
Workplace
We offer
ETH Zurich is a family-friendly employer with excellent working conditions. You can look forward to an exciting
working environment, cultural diversity and attractive offers and benefits.
chevron_right Working, teaching and research at ETH Zurich
We value diversity
In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value
diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students
are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open
environment that allows everyone to grow and flourish.
Curious? So are we.
We look forward to receiving your online application including:
- CV
- publication list
- a motivation letter, highlighting your scientific background and experience relevant to the project and explaining
your excitement about translational synthetic biology, AAVs, and gene therapy.
- two letters of recommendation
Please note that we exclusively accept applications submitted through our online application portal. Applications via
email or postal services will not be considered. For additional questions please contact Ana Palma Teixeira by mail
(anapa@ethz.ch).
We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial
intelligence.
About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our
excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000
people from more than 120 countries find our university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we
work together to develop solutions for the global challenges of today and tomorrow.
About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our
excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000
people from more than 120 countries find our university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we
work together to develop solutions for the global challenges of today and tomorrow.
100%, Basel, fixed-term
print Drucken
The Biotechnology and Bioengineering group at the Department of Biosystems Science and Engineering (D-BSSE) of ETH
Zurich in Basel is looking for scientists who are eager to make a difference. If you're someone who thrives on
innovation and wants to be part of something new and exciting, we'd love to hear from you! We're on the lookout for
talented individuals to join us in launching a new venture focused on cutting-edge research in scalable recombinant
Adeno-associated virus (rAAV) manufacturing and closed-loop gene therapies for inborn metabolic disorders.
The D-BSSE is a special place where different fields of study come together in a beautiful harmony. It's the first of
its kind at the Swiss Federal Institute of Technology, ETH Zurich, and its mission is to encourage progress in the
fields of Systems Biology, Biotechnology, and Synthetic Biology. Here, groups working on theoretical biology,
experimental biology, and engineering work together, sharing their passion and knowledge to make the world a better
place. The D-BSSE is based in beautiful Basel, Switzerland. It's right in the heart of the Biovalley, a tri-national
region that's home to 40% of the global life science industry. This includes several pharma giants, which makes it a
special place for high-leverage translational research.
Project background
Our group uses state-of-the-art Synthetic Biology principles to engineer human cells and develop advanced gene and
cell therapies targeting cancer, as well as metabolic, neurodegenerative, autoimmune and infectious diseases. For more
information, please consult our webpage and published work.
Job description
We're working on a really exciting project together! Our goal is to take synthetic biology tools and turn them into
amazing new AAV-based therapies. We're striving to make them safer, more effective, and easier to produce in large
quantities. We're working hard to overcome some of the challenges we face in the gene therapy field. This includes
finding ways to produce large amounts of AAV vectors, as well as creating gene therapies that can adjust to the signs
of diseases and keep the levels of the therapeutic protein just right. You'll get to be a part of developing,
validating, and integrating these technologies, and help shape the roadmap towards clinical translation.
Profile
We're on the lookout for exceptional scientists who are passionate about commercializing startup technologies. You're
a creative and highly motivated scientist who does well in a high-power scientific environment. You're excited by the
opportunity to create and implement cutting-edge technologies. In addition, you have:
- A PhD in synthetic biology, bioengineering, biotechnology or a related field
- A proven track and publication record in academia or industry
- Experience with mammalian cell engineering, AAV vector design, production, and purification, synthetic gene circuits
and inducible expression systems, high-throughput screening and advanced molecular cloning, and in vivo preclinical
models
- A strong entrepreneurial mindset
- A collaborative, motivated and excelling attitude
Workplace
Workplace
We offer
ETH Zurich is a family-friendly employer with excellent working conditions. You can look forward to an exciting
working environment, cultural diversity and attractive offers and benefits.
chevron_right Working, teaching and research at ETH Zurich
We value diversity
In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value
diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students
are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open
environment that allows everyone to grow and flourish.
Curious? So are we.
We look forward to receiving your online application including:
- CV
- publication list
- a motivation letter, highlighting your scientific background and experience relevant to the project and explaining
your excitement about translational synthetic biology, AAVs, and gene therapy.
- two letters of recommendation
Please note that we exclusively accept applications submitted through our online application portal. Applications via
email or postal services will not be considered. For additional questions please contact Ana Palma Teixeira by mail
(anapa@ethz.ch).
We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial
intelligence.
About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our
excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000
people from more than 120 countries find our university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we
work together to develop solutions for the global challenges of today and tomorrow.
About ETH Zürich
ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our
excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000
people from more than 120 countries find our university to be a place that promotes independent thinking and an
environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we
work together to develop solutions for the global challenges of today and tomorrow.